Information AboutTriflate |
| CATEGORIES ABOUT TRIFLATE | |
| functional groups | |
| leaving group | |
| anions | |
| SHOPPER'S DELIGHT | |
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Triflate, more formally known as '''trifluoromethanesulfonate''', has the molecular formula CF3SO3-. It is an extremely stable Polyatomic Ion , being the Conjugate Base of '''triflic acid''' (CF3SO3H), one of the strongest Acid s known and a Super Acid . A triflate is an excellent Leaving Group used in certain Organic Reactions such as Nucleophilic Substitution , Suzuki Coupling s and Heck Reaction s. For example, in an alkyl triflate such as ''n''- Butyl triflate, (CH3CH2CH2OTf), the "OTf" is used to designate the triflate leaving group. Since alkyl triflates are extremely reactive in SN2 Reactions , they must be stored in conditions free of Nucleophile s (such as Water ). Tf represents the trifyl group, CF3SO2-. A mild triflating reagent is '''phenyl triflimide''' or N,N-Bis(trifluoromethylsulfonyl)aniline. See Trifluoromethanesulfonic Acid |