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ART treatments are relatively new and have been around for only around three decades. There is some evidence that children born of ART have higher rates of genetic mutation than children conceived naturally. This is most apparent in children born after ICSI treatment, where a single sperm is injected directly into an egg. ICSI uses a random sperm, avoiding the natural selection process, where any sperm that can't reach the egg dies. After ICSI around 7% of children born have a severe genetic defect as opposed to less than 4% conceived spontaneously. REFERENCES |