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''Vero cells'' are used in cell cultures for many purposes, including:
  • screening for the toxin of '' E. Coli '', first named ''Vero toxin'' after this cell line, and later called '' Shiga-like Toxin '' due to its similarity to Shiga Toxin isolated from '' Shigella Dysenteriae ''.

  • as host cells for growing virus; for example, to measure replication in the presence or absence of a research pharmaceutical, or testing for the presence of Rabies virus.


The Vero cell lineage is continuous and Aneuploid . A Continuous Cell Lineage can be replicated through many cycles of division and not become senescent. Aneuploidy is the characteristic of having an abnormal number of Chromosomes .


Lineages


  • ''Vero'' ( ATCC No. CCL-81 )

    • Isolated from ''C. aethiops'' kidney on 27 Mar 1962.





Bibliography

  • ''Yasumura,Y. and Kawakita,M. The research for the SV40 by means of tissue culture technique, Nippon Rinsho, 21(6): 1201-1219, 1963''. {Link without Title}


  • ''Fundamental Techniques in Cell Culture ...a Laboratory Handbook, Sigma, Sec 5.2, Continuous Cultures.'' {Link without Title}


  • ''History and Characterization of the Vero Cell Line -- A Report prepared by CDR Rebecca Sheets, Ph.D., USPHS CBER/OVRR/DVRPA/VVB for the Vaccines and Related Biological Products Advisory Committee Meeting to be held on May 12, 2000 OPEN SESSION'' www.fda.gov pdf