- Benjamin Agosto , figure skater
- Christina Aguilera , pop singer
- Isabel Allende , writer
- Roberto Alomar , baseball player
- Sandy Alomar , baseball player, younger brother of Roberto Alomar
- Julia Alvarez , writer
- Luis Walter Alvarez , Nobel Prize-winning physicist
- Rudolfo Anaya , writer
- Desi Arnaz , actor
- Ricardo Sanchez , Lieutenant General
- Judy Baca , artist
- Joan Baez , folk singer and activist
- David Barkley , soldier and Medal of Honor recipient
- Jean-Michel Basquiat , artist
- Ruben Blades , actor
- Kimberly Alexis Bledel , actress
- Ryan Cabrera , singer
- Elsa Salazar Cade , entomologist and educator
- Fernando Caldeiro , astronaut
- Jose Canseco , baseball player
- Mariah Carey , artist
- Lynda Carter , actress
- Franklin Chang-Diaz , astronaut
- Cesar Chavez , labor leader
- Dennis Chavez , senator
- Linda Chavez , conservative commentator
- Linda Chavez-Thompson , labor leader
- Henry Cisneros , U.S. Secretary of Housing and Urban Development
- Sandra Cisneros , writer
- Roberto Clemente , baseball player
- George Clooney , actor
- Anderson Cooper , journalist (part decendant from Spain)
- Sammy Davis, Jr. , singer, actor
- Oscar De La Hoya , boxer
- Fernando Del Bosque , explorer
- Dolores Del Rio , actress
- Cameron Diaz , actress
- Gloria Estefan , singer
- Emilio Estevez , actor
- Stacy Ferguson , singer
- Miguel Ferrer , actor
- Rudy Galindo , figure skater
- Andy Garcia , actor
- Jerry Garcia , musician
- Ruben Garcia Jr. , Assistant Executive Director FBI
- Rupert Garcia , artist
- Ernesto Galarza , labor organizer, author
- Roberto C. Goizueta , businessman
- Scott Gomez , hockey player
- Alberto Gonzales , U.S. Attorney General
- Pancho Gonzalez , tennis player
- Roberto Guerrero , racing driver
- Sidney M. Gutierrez , astronaut
- Salma Hayek , actress
- Rita Hayworth , actress
- Joseph Marion Hernandez , U.S. congressman
- Jose Hernandez , astronaut
- Keith Hernandez , baseball player
- Oscar Hijuelos , writer
- Maria Hinojosa , journalist
- Dolores Huerta , labor leader
- Eliseo Iglesias , musician
- Raul Julia , actor
- Joanna Kerns , actress
- Emeril Lagasse , chef, TV personality
- John Leguizamo , actor, comedian
- Jose Limon , modern dancer and choreographer
- Jennifer Lopez , actress, singer
- Michael Lopez-Alegria , astronaut
- Nancy Lopez , golfer
- Trini Lopez , singer
- Christopher Loria , astronaut
- Juan Marichal , baseball player
- Rosario Marin , United States treasurer
- Ricky Martin , singer
- Melquiades Martinez , U.S. Secretary for Housing and Urban Development
- Pedro Martinez , baseball player
- Mario Molina , Nobel Prize-winning chemist
- Ricardo Montalban , actor
- Rita Moreno , actress, singer, dancer
- Anthony Munoz , football player
- Carlos Noriega , astronaut
- Antonia Novello , U.S. Surgeon General
- Ellen Ochoa , astronaut
- Severo Ochoa , Nobel Prize-winning biochemist
- John Olivas , astronaut
- Edward James Olmos , actor
- Rosie Perez , actress
- Freddie Prinze , comedian
- Freddie Prinze Jr. , actor
- Anthony Quinn , actor
- José Quintero , theater director
- Juan Bautista Rael , ethnographer and folklorist
- Bill Richardson , Governor of New Mexico
- Gabriel Rios , pop singer
- Geraldo Rivera , talk-show host, journalist
- Alex Rodriguez , baseball player
- Chi Chi Rodriguez , golfer
- Linda Ronstadt , singer
- John Ruiz , boxer
- Alberto Salazar , marathoner
- Carlos Santana , guitarist, singer
- Luis Santeiro , writer
- Selena , singer
- Junípero Serra , missionary
- Richard Serra , sculptor
- Charlie Sheen , actor
- Martin Sheen , actor; father of Charlie Sheen and Emilio Estevez
- Jimmy Smits , actor
- Sammy Sosa , baseball player
- Gary Soto , writer
- Nydia Velásquez , U.S. Representative
- Lupe Velez , actress
- Raquel Welch , actress
- Ted Williams , baseball player
- George D. Zamka , astronaut
|
