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Domoic acid, also called '''Amnesic Shellfish Poison''' (ASP), is an Amino Acid phycotoxin (algal toxin) found associated with certain Algal Bloom s {Link without Title} .

In ;"Doumoi" is used as an Anthelmintic in Tokunoshima, Kagoshima .

Domoic acid is also produced by in Marine organisms that feed on the Phytoplankton , such as Shellfish , Anchovies , and Sardine s. In Mammal s, including Human s, domoic acid acts as a Neurotoxin , causing short-term Memory loss, Brain damage, and Death in severe cases. Red Tide s are associated with the phenomenon of ASP.

In the brain, domoic acid especially damages the Hippocampus and Amygdaloid Nucleus . It damages the Neuron s by activating AMPA and Kainate receptors, causing an influx of Calcium . Although calcium flowing into cells is a normal event, the uncontrolled increase of calcium causes the cell to degenerate.