- CGI Group Inc. , the Canadian information management company (formerly ''Conseillers en Gestion et Informatique C.G.I. Inc.'').
- Common Gateway Interface , a technology used in web servers.
- --- CGI.pm , a Perl module used for dealing with it.
- Computer-generated Imagery , a movie-making technology.
- Computer Graphics Interface , a low-level interface between the Graphical Kernel System and the hardware.
- Clinical Global Impression , a scale to assess treatment response associated with mental disorders.
- Corrugated Galvanised Iron , moulded sheet-metal.
- Consultative Group On Indonesia
- Cape Girardeau Regional Airport (IATA airport code: CGI) in Cape Girardeau, Missouri, United States.
- Cuerpo Guardia De InfanterÃa , an Argentine Police Riot Control Service .
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