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Urinary Tract Infection




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A urinary tract infection ('''UTI''') is an Infection of the Urinary Tract . An infection anywhere from the Kidney s to the Ureter s to the Bladder to the Urethra qualifies as a urinary tract infection.


SYMPTOMS & SIGNS



DIAGNOSIS

A patient with Dysuria (painful voiding) and urinary frequency generally has a spot mid-stream urine sample sent for Urinalysis , specifically the presence of Nitrite s, Leukocyte s or Leukocyte Esterase . If there is a high bacterial load without the presence of leukocytes, it is most likely due to contamination. Pyelonephritis is ruled out by checking for Costovertebral Angle Tenderness (CVAT). The diagnosis of UTI is confirmed by a urine Culture .

If the urine culture is negative:

In severe infection, characterised by Fever , Rigor s or flank pain, Urea and Creatinine measurements may be performed to assess whether Renal Function has been affected.


CAUSATIVE AGENTS

Common organisms that cause UTIs include: '' Escherichia Coli '' and '' Staphylococcus Saprophyticus ''. Less common organisms include '' Proteus Mirabilis '', '' Klebsiella Pneumoniae '', and '' Enterococcus '' spp.

A Mnemonic that can be used to remember the bacteria that cause UTIs is SEEK PP (''Staph saprophyticus'', ''E. coli'', ''Enterococcus'', ''Klebsiella'', ''Proteus'', '' Pseudomonas '').


PREVENTION

The following are a list of things that can be done to avoid a urinary tract infection. As many people, especially women, experience recurrent infections some commonly recommended preventative measures are:


EPIDEMIOLOGY

UTIs are most common in sexually active women, and increase in Diabetics and people with Sickle-cell Disease or anatomical malformations of the urinary tract.

The use of Urinary Catheter s in both men and women who are elderly, people experiencing nervous system disorders and people who are convalescing or unconscious for long periods of time may result in an increased risk of urinary tract infection for a variety of reasons. Scrupulous aseptic technique may decrease this risk.

Women are more prone to UTIs than males because in females, the Urethra is much shorter and closer to the Anus than in males. The article on Vulvovaginal Health has some health tips for preventing UTIs.

A common cause of UTI is an increase in sexual activity, such as vigorous sexual intercourse with a new partner. The term "honeymoon cystitis", although somewhat demeaning, has been applied to this phenomenon {Link without Title} .


TREATMENT

Most uncomplicated UTIs can be treated with oral Antibiotic s such as Trimethoprim , Cephalosporin s, Macrodantin , or a Fluoroquinolone (e.g. Ciprofloxacin , Levofloxacin ). (Whilst Co-trimoxazole was previously used (and continues to be used in the U.S.), the additional benefits of the Sulphonamide gave little additional benefit compared to the trimethoprim component alone, but was responsible for its both high incidence of mild allergic reactions and rare but serious complications).

If the patient has symptoms consistent with Pyelonephritis , Intravenous antibiotics may be indicated.


Recurrent UTIs

Patients with recurrent UTIs may need further investigation. This may include Ultrasound scans of the kidneys and bladder or Intravenous Urography (X-rays of the urological system following intravenous injection of iodinated contrast material).

Often long courses of low dose antibiotics are taken at night to help prevent otherwise unexplained cases of recurring cystitis.

Acupuncture has been shown to be effective in both treating urinary tract infections, (sometimes along with chinese herbs with antibiotic compounds) as well as preventing new infections in chronic cases1 ''(cf acupuncture group, x2 incidents in the sham group, x3 in the control group)''
2
3 ''(highlights need for considering different TCM diagnostic categories in acupuncture research)''
. A study published in October 2002 in the American Journal of Public Health showed that urinary tract infection occurrence was reduced by 50% for 6 months4
. Acupuncture appears to reduce the total amount of residual urine in the bladder.

If there is no response to treatments, Interstitial Cystitis may be a possibility.


REFERENCES



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