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| align="center" colspan=2 | Years:
1521 1522 1523 - 1524 - 1525 1526 1527
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| align="center" colspan=2 | 1500s 1510s - 1520s ''' - 1530s 1540s 1550s
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| align="center" | - 16th Century ''' - 17th Century
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Events
Births
- February 10 - Albrecht Giese IV , German politician and diplomat (died 1580 )
- February 17 - Charles Of Guise , French cardinal (d. 1574 )
- May 28 - Selim II , Ottoman Sultan (died 1574 )
- August 23 - François Hotman , French protestant lawyer and writer (died 1590 )
- September 7 - Thomas Erastus , Swiss theologian (died 1583 )
- September 11 - Pierre De Ronsard , French poet (died 1585 )
- Jan Borukowski , royal secretary of Poland (died 1584 )
- Armand De Gontaut, Baron De Biron , French soldier (died 1592 )
- Azai Hisamasa , Japanese warlord (died 1573 )
- Diego De Landa , Bishop of the Yucatán (died 1579 )
- Jean Pithou , French lawyer and author (died 1602 )
- Nicolas Pithou , French lawyer and author (died 1598 )
- Tahmasp I , Shah Of Persia
- Thomas Tusser , English poet and farmer (died 1580 )
Deaths
- January 5 - Marko Marulic , Croatian poet (born 1450 )
- April 30 - Pierre Terrail, Seigneur De Bayard , French soldier (b. 1473 )
- May 21 - Thomas Howard, 2nd Duke Of Norfolk , English soldier and statesman (born 1443 )
- May 23 - Ismail I , Shah Of Persia (born 1487 )
- July 20 - Claude Of France , queen of Louis XII Of France (born 1499 )
- December 20 - Thomas Linacre , English humanist and physician (born 1460 )
- December 24 - Vasco Da Gama , Portuguese explorer
- Diego Velázquez De Cuéllar , Spanish conquistador (born 1465 )
- Hans Holbein The Elder , German painter (born 1460 )
- Joachim Patinir , Flemish painter
- William Scott Of Scott's Hall , Lord Warden of the Cinque Ports
- Andrea Solari , Italian painter
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