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As Theodosius was an only child, and his mother Thermantia was his father's first and only wife, Serena's mother or father must have been from an earlier marriage of Thermantia, thus making her only a half-niece of Theodosius. (Theodosius was not an only child. He had an elder brother, Honorius,who had two daughters, Serena and Thermantia, both of whom were adopted by Theodosius and taken by him to Constantinople when his brother died.)