- ''Regina'', Latin word for Queen .
- Juno Regina, queens of the gods in Roman mythology.
- ''Regina'', the Italian word for queen, derived directly from the Latin above.
- Regina, Saskatchewan , the capital of the Canadian Province of Saskatchewan .
- Regina , a former Canadian federal Electoral District in the province of Saskatchewan.
- HMCS ''Regina'' , a ''Halifax''-class frigate of the Canadian Navy
- Regina, New Mexico
- Regina (saint) Catholic martyr
- Saint Regina ecclesiastical division in Saskatchewan
- Rexx , open-source REXX interpreter for Linux, BSD, Windows, etc.
- Regina Encarnacion Ansong Velasquez , also known as Regine Velasquez (''Asia's Songbird''), is a singer, actress, model, entrepreneur, concert and stage director, and record producer from the Philippines .
- Popular singer Regina (Regina Richards) , whose only hit song, "Baby Love", reached #10 in the U.S. in 1986.
- Regina , a concubine of Charlemagne
- Regina (program) , a suite of mathematical software for 3-manifold topologists.
- Regina, Regina , a country music duo in the mid 90's.
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