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Phosphodiesterase




PDEs are responsible for the degradation of the Cyclic Nucleotide s CAMP and CGMP . They are therefore important regulators of Signal Transduction mediated by these molecules.

Inhibitors Of PDE can prolong or enhance the effects of physiological processes mediated by these cyclic nucleotides. Please see CGMP-specific PDE5 and PDE5 Inhibitor for more details.