may mean:
- Orion (company) , supplier of consumer electronics and white goods from Hungary
- Orion Beer , a beer manufacturing company based in Okinawa, Japan
- Orion Bus Industries , a subsidiary of DaimlerChrysler, based in Oriskany, New York
- Orion Confectionery , a company in Seoul, Korea
- Orion Electric , an electronics manufacturer based in Fukui, Japan
- Orion Group , a company in Korea
- Orion Health , a Health IT company in Auckland, New Zealand
- Orion Multisystems , a personal supercomputer company in the US (defunct As Of 2006 ) {Link without Title}
- Orion Optics , a telescope manufacturer in the UK
- Orion Pictures , a defunct movie company
- Orion Publishing Group , owned by Hachette Livre
- Orion Telecommunications , a telecommunications company based in Australia
- Orion, a car audio company until bought by Directed Electronics
- Orion Expedition Cruises , a cruise line based in Australia
- Orion (comics) , a comic book character, the son of Darkseid, in the DC Comics universe
- Orion (manga) , the Manga by Masamune Shirow
- Orion (novel) , a 1978 novel by G.B. Giorgio ( Gail Brewer-Giorgio )
- Orion (Star Trek) , an extraterrestrial race in the fictional ''Star Trek'' universe
- ORION Foundation , a fictional intelligence organization from the TSR, Inc. role-playing game Top Secret/S.I..
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- Orion, extraterrestrial race of humanoid cats from David Weber and Steve White's novel The Shiva Option
- Orion, the name of a white and orange cat in the first '' Men In Black '' film
- Raumpatrouille Orion , a German science fiction series
- ''Orion'' , a fictional spaceship in the Stargate universe
- Orion.78 , a song in the Dance Dance Revolution series
- Orion (song) , an instrumental piece in the ''Master of Puppets'' album by Metallica
- Orion (singer) , stage name of American singer Jimmy Ellis, who dressed and sang in the manner of Elvis Presley following Presley's death
- Ford Orion , an automobile model of the Ford Motor Company
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