- Grace Abbott -- social reformer and social worker.
- Hartley Burr Alexander -- Anthropologist, poet, philosopher, educator, and authority on North American Indian mythology.
- Bess Streeter Aldrich -- A successful author of the early 1900s who lived in Elmwood, Nebraska.
- William Jennings Bryan -- American political leader.
- Willa Cather -- Author who grew up in Nebraska.
- William Frederick Cody , famous as " Buffalo Bill " -- Soldier, buffalo hunter, Army scout, actor, rancher, irrigationist, and showman of the West.
- Edward Creighton -- Telegraph pioneer and banker.
- Loren Eisley -- Respected anthropologist, poet, and philosopher of science.
- Edward J. Flanagan -- Founder of Boys Town.
- Robert W. Furnas -- Newspaperman, soldier, historian, and politician.
- Nathan J. Gold -- Businessman, civic leader, philanthropist, and Nebraska booster.
- Dwight Palmer Griswold -- Banker, publisher, and politician.
- Gilbert M. Hitchcock -- Founder of the Omaha World-Herald and politician.
- J. Sterling Morton -- Father of Arbor Day, U.S. Secretary of Agriculture, legislator, and Nebraska territorial secretary.
- John Gneisenau Neihardt -- Epic poet of the West, historian, philosopher, and friend of the American Indian. Neihardt was named Nebraska Poet Laureate in 1921.
- George William Norris -- An American political leader who represented Nebraska in Congress.
- John J. Pershing -- Commanding General, American Expeditionary Forces, Europe, during World War I and US Army Chief of Staff.
- Nathan Roscoe Pound -- Botanist, pioneer ecologist, lawyer, and legal educator.
- Mari Sandoz -- Author, historian, and friend of the Indian.
- Standing Bear -- Ponca Indian chief, symbol for Indian rights.
- Arthur Weimar Thompson -- Auctioneer.
- Susette LaFlesche Tibbles -- Omaha Indian, also known as "Inshata Theumba" or "Bright Eyes," speaker and writer for Indian rights.
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