is a highway in northeast
Missouri . Its northern terminus is at the
Iowa state line (about thirteen miles north of
Memphis where it continues as
Iowa State Highway 15 ; its southern terminus is at
U.S. Route 54 in
Mexico .
Missouri 15 is one of the original
1922 Missouri highways, though its southern terminus was significantly farther at
Missouri State Highway 71 (now
U.S. Route 65 ) at
Buffalo . It was replaced by
U.S. Route 54 from Mexico to southwest of
Macks Creek and by
Missouri State Highway 73 from that point to Buffalo.
