- Cricketers
- --- M. J. K. Smith , English cricketer
- --- M. J. Smith , cricketer who played for Middlesex CCC and England
- --- Michael Jonathon Smith , Scottish cricketer
- --- A.M. (Mike) Smith , Gloucestershire CCC and England cricketer
- Basketball players
- --- Michael Smith (basketball) , former NBA basketball player from Washington, D.C.
- --- Mike Smith (basketball) , professional basketball player from West Monroe, Louisiana
- --- Mike Smith (basketball Commentator) , former pro player and current Los Angeles Clippers television and radio commentatator
- Mike Smith (football Manager) , twice Wales national football team manager and manager of Hull City A.F.C.
- Mike Smith (jockey) , American jockey
- Michael Smith (chef) , Canadian celebrity chef.
- Michael Smith (chemist) (1932-2000), Canadian Nobel-prize winning chemist
- Michael Smith (Bishop) , Catholic Bishop of Meath, Ireland
- Michael J. Smith , astronaut
- Michael Smith (philosopher)
- Michael Smith (poet)
- Michael Smith (Irish Politician) (b. 1940), Republic of Ireland politician
- Michael Hoke Smith , (1855–1931) American politician
- Mike Smith (actor) (b. 1972), Canadian actor and guitarist. Portrays Bubbles in the television show Trailer Park Boys
- Mike Smith , chair of CVC Capital Partners
- Michael Smith (banker) - CEO Hongkong And Shanghai Banking Corporation
- Michael Keith Smith of the UK Conservative Democratic Alliance
- Michael K. Smith (Vermont) - as of early 2006, the secretary of Human Services for the state of Vermont
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