False Discovery Rate , a statistical method for dealing with the multiple comparisons problem
Flight Data Recorder , a device used to record aircraft and pilot behavior in order to analyze accidents (usually called " Black Box es" by the news media).
FDR resp. FDR2 - A software to check formal models expressed in Communicating Sequential Processes , developed by Formal Systems (Europe) Ltd..
FDR Drive (full name: Franklin D. Roosevelt Drive), a highway named for the U.S. president that runs along the East River in Manhattan, New York City.