is the presence of abnormal
Protein s in the
Bloodstream which thicken or gel on exposure to
Cold .
These proteins may be present in
Mycoplasma Pneumonia ,
Multiple Myeloma , certain
Leukemia s, primary
Macroglobulinemia , and some
Autoimmune Disease s, such as
Systemic Lupus Erythematosus and
Rheumatoid Arthritis . This is also found occasionally as a symptom in 35% of chronic hepatitis C infections (Pascual ''et al'' 1990).
- Pascual M, Perrin L, Giostra E, Schifferli JA. ''Hepatitis C virus in patients with cryoglobulinemia type II.'' J Infect Dis 1990;162:569-570. PMID 2115556.
