Celexa Website Links For
Citalopram
 

Information About

Celexa




  Bgcolor "#ffffff" align="center" colspan="2"
  Align "center" colspan="2" '' IUPAC Chemical Name ''
  - Align "center" style="border-bottom: 3px solid gray"
  ''' "http://wwwinformationdelightinfo/encyclopedia/entry/CAS_number" class="copylinks">CAS Number ''' <br/> 59729-33-8
  ''' "http://wwwinformationdelightinfo/encyclopedia/entry/ATC_code" class="copylinks">ATC Code ''' <br/> N06AB04
  Bgcolor "#eeeeee" Chemical Formula
  Bgcolor "#ddeeff" C<sub>20</sub>H<sub>22</sub>FN<sub>2</sub>O
  Bgcolor "#eeeeee" Molecular Weight
  Bgcolor "#ddeeff" 40535
  Bgcolor "#eeeeee" Bioavailability
  Bgcolor "#ddeeff" 80% compared to IV administration
  Bgcolor "#eeeeee" Metabolism
  Bgcolor "#ddeeff" CYP3A4 and CYP2C19 Predominantly
  Bgcolor "#eeeeee" Elimination Half-life
  Bgcolor "#ddeeff" 85% hepatic clearance, and 15% renally
  Bgcolor "#eeeeee" Excretion
  Bgcolor "#ddeeff" Mostly as unmetabolized Citalopram, partly DCT and traces of DDCT
  Bgcolor "#eeeeee" Pregnancy Category
  Bgcolor "#ddeeff" C
  Bgcolor "#eeeeee" Legal Status
  Bgcolor "#ddeeff" Free to Market patent expired
  Bgcolor "#eeeeee" Routes of administration
  Bgcolor "#ddeeff" Oral





Citalopram is sold as a Racemic mixture, consisting of 50% ''R''-(−)-citalopram and 50% ''S''-(+)-citalopram. Only the ''S''-(+) enantiomer has the desired antidepressant effect. Lundbeck now markets the pure ''S''-(+) enantiomer, the generic name of which is Escitalopram . Escitalopram is sold as the Oxalate - that is, the Nitrogen atoms of the tertiary Amine functional groups of two ''S''-(+)-citalopram molecules are protonated by Oxalic Acid to form two escitalopram Ammonium Cation s and an oxalate Anion .









EXTERNAL LINKS

Pharmacological information and treatment study information:

Lunbeck's official websites for citalopram under the trade name Cipramil:
  • http://www.cipramil.com


Forest's official websites for citalopram under the trade name Celexa: