BUFFALO is also an acronym for ''Bit User Fast Friendly Aid to Logical Operations'', a monitor program for the Freescale 68HC11 microcontroller.
Buffalo was at one time the proposed name for a province in Western Canada that would have encompassed what is now Alberta and Saskatchewan, both of which emerged instead in 1905.
Buffalos are Belgians who immigrated to America in the early 20th century. They traveled through the city of Buffalo on their way to Detroit and Chicago.