The following is a list of the ranked by healthcare revenue. Some companies (eg, Bayer ) have additional Chemicals revenue not included here. The phrase '''Big Pharma''' is often used to refer to companies with revenue in excess of $3 billion, and/or R&D expenditure in excess of $500 million, and represents the first 30 or so companies in this list.
Source: ''Top 50 pharmaceutical companies'', MedAdNews , September 2005
- 3M , a diversified global technology company based in the United States which produces pharmaceuticals as part of its health care business
- Abbott Laboratories , a top-20 pharma company based in the United States
- Able Laboratories ( external link ), a former American generic pharmaceutical manufacturer which entered Bankruptcy in 2005
- Aburaihan ( external link ), the largest Iranian pharmaceutical manufacturer
- Alkermes , an American company
- Allergan , an American multinational
- Almirall Prodesfarma , a Spanish multinational
- Alphapharm , an Australian generic pharmaceutical manufacturer and a wholly-owned subsidiary of Merck KGaA
- Altana Pharma AG , formerly Byk Gulden, part of Altana AG, a German maker of chemicals and pharmaceuticals
- ALZA Corporation , an American company acquired by Johnson & Johnson in 2001
- Amgen , a top-20 pharma company based in the United States
- Astellas Pharma , a Japanese company formed in 2005 through the merger of Fujisawa Pharmaceutical and Yamanouchi Pharmaceutical
- Astra AB, a former Swedish company which in 1999 merged with Zeneca Group PLC to form AstraZeneca
- AstraZeneca , a top-20 pharma company based in the United Kingdom formed in 1999 through the merger of Astra AB and Zeneca Group PLC
- Aventis , a former French company which in 2004 merged with Sanofi-Synthélabo to form Sanofi-Aventis
- Bakhtar Bioshimi ( external link ), an Iranian generic pharmaceutical manufacturer
- Bayer , a top-20 pharma company based in Germany
- Biogen Idec , an American company formed in 2003 through the merger of Biogen and Idec Pharmaceuticals
- Biolex , an American company
- BioPort , an American vaccine manufacturer and a subsidiary of Emergent BioSolutions
- Biotecnol , a Portuguese company
- Biovail , the largest Canadian harmaceutical company
- Boehringer-Ingelheim , a top-20 pharma company based in Germany
- Bristol-Myers Squibb , a top-20 pharma company based in the United States
- Catalytica, a former American company which merged with Synotex Company in 2000 to form DSM Catalytica Pharmaceuticals, now known as DSM Pharmaceuticals
- CCL Pharmaceuticals ( external link ), a Pakistani company
- Celltech, a former British company acquired by the Belgian company UCB in 2004
- Century Pharmaceuticals ( external link ), an Indian company
- Cephalon ( external link ), an American company known for the narcolepsy drug, Modafinil
- Cipla , an Indian company best known as a manufacturer of anti-AIDS drugs
- Claris Lifesciences ( external link ), a multinational based in India
- Daiichi Pharmaceuticals, a former Japanese company which merged with Sankyo Co., Ltd. in 2005 to form Daiichi Sankyo
- Daiichi Sankyo ( external link ), a Japanese holding company formed in 2005 through the merger of Sankyo Co., Ltd. and Daiichi Pharmaceuticals
- Diosynth , a former Dutch company acquired in 2005 by the American firm Organon International , which is in turn a part of the Dutch Akzo Nobel
- Douglas Pharmaceuticals ( external link ), a New Zealand-based company
- Dow Pharmaceutical Sciences ( external link ), an American company focused on topical therapeutics
- DSM Pharmaceuticals
- Eli Lilly And Company , a top-20 pharma company based in the United States
- Ethypharm ( external link ) a French company specialized in the development of drug delivery solutions for the pharmaceutical industry
- Genentech , an American biopharmaceutical company, considered to have founded the biotechnology industry as a whole
- Genzyme , an American company
- Gilead Sciences , an American biopharmaceutical company
- GlaxoSmithKline , a top-20 pharma company based in the United Kingdom
- GPC Biotech , a German biopharmaceutical company
- Grindex external link , the largest pharmaceutical company in the Baltic States.
- Hexal Australia , an Australian generic pharmaceutical manufacturer, part of the Hexal International Group
- Hexal International Group ( external link ), a German generic pharmaceutical manufacturer
- Hoffmann-La Roche , or Roche, a top-20 pharma company based in Switzerland
- ICN Pharmaceuticals, now known as Valeant
- Institute For OneWorld Health , a nonprofit American pharmaceutical company focused on developing infectious disease drugs for developing countries
- Ipsen ( external link ), a French company
- Isis Pharmaceuticals ( external link ), an American company focused on development of RNA-based therapeutics
- Janssen Pharmaceutica Products, a subsidiary of Johnson & Johnson
- Janssen-Cilag, a subsidiary of Johnson & Johnson
- Jelfa SA ( external link ), a Polish generic pharmaceutical manufacturer
- Johnson & Johnson , a top-20 pharma company based in the United States
- King Pharmaceuticals , an American company
- Knoll Pharmaceuticals, formerly the pharmaceutical division of BASF , acquired by Abbott in 2001
- Krka, D. D. , a Slovenian generic pharmaceutical and cosmetics manufacturer
- Kurve Technology, Inc. ( external link ) an American company specialized in the development of drug delivery solutions for the pharmaceutical industry
- LEO Pharma , a Danish pharmaceutical company
- Lundbeck , a Danish company
- Sanofi-Aventis , a global top-20 pharma company based in France
- Schering , a German company
- Schering-Plough , an American company created during World War II through seizure of assets from Schering
- Serono , a Swiss biopharmaceutical company
- Servier Laboratories
- Shire Pharmaceuticals Group , a British company
- Solvay Group
- Sugen, purchased by Pfizer in 2003
- Takeda , a top-20 pharma company based in Japan
- TAP Pharmaceutical Products, Inc ( external link ), a joint-venture of Abbott and Takeda , created without discovery or manufacturing capabilities
- UCB , a Belgian biopharmaceutical company
- Upsher-Smith Laboratories ([http://www.upsher-smith.com/ external link]), a branded generic manufacturer
- Valeant , formerly ICN Pharmaceuticals, an American company
- Vertex Pharmaceuticals , an American company
- Wyeth , formerly American Home Products, a top-20 pharma company based in the United States
- Xencor ( external link ), a biopharmaceutical company without marketed products as of April 2006
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