Information AboutBasophil Granulocyte |
| CATEGORIES ABOUT BASOPHIL GRANULOCYTE | |
| cell biology | |
| granulocytes | |
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SECRETIONS When activated, basophils secrete Histamine , several Proteoglycan s, Lipid mediators like Leukotriene s, and several Cytokine s. Histamine and proteoglycans are pre-stored in the cell's granules while the other secreted substances are newly generated. Each of these substances contributes to inflammation. Recent evidence suggests that basophils are an important source of the cytokine, Interleukin-4 , perhaps more important than T Cells . Interleukin-4 is considered one of the critical cytokines in the development of allergies and the production of IgE antibody by the immune system. There are other substances that can activate basophils to secrete which suggests that these cells have other roles in inflammation. |
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