- Babe: eurodance music artist
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- the '', or to their title character.
- Babe, Portugal , a parish in Portugal .
- Babe Ruth , American Baseball player and United States national icon.
- a number of other early 1900s athletes, both before and after Babe Ruth, including these among many others:
- --- Babe Adams (baseball)
- --- Babe Herman (baseball)
- --- Babe Pinelli (baseball)
- --- Babe Pratt (ice hockey)
- --- Babe Dye (ice hockey)
- Babe Didrikson , an American multi-sport female Athlete .
- a nickname for American film actor Oliver Hardy , used by his family and friends
- a nickname for American film actor Curly Howard , used by his family and friends
- any good looking woman. (i.e., "She's a babe!")
- a nickname for a romantic partner. In most cases, similar to "Honey", "Sweetie" (or "Baby").
- a synonym for Infant
- '' Babe '', a comic book by artist/writer John Byrne
- the giant blue ox given to Paul Bunyan in the Tall Tale about the Mythical Lumberjack
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