April 22 is the 112th day of the year in the Gregorian Calendar (113th in Leap Year s). There are 253 days remaining.
- 1500 - Portuguese Navigator Pedro Álvares Cabral becomes the first European to sight Brazil .
- 1509 - Henry VIII ascends the Throne of England after the death of his father.
- 1529 - Treaty Of Saragossa divides the eastern hemisphere between Spain and Portugal along a line 297.5 leagues or 17° east of the Moluccas .
- forces under Texas General Sam Houston capture Mexican General Antonio López De Santa Anna .
- begins – troops under Union Colonel Benjamin Grierson attack central Mississippi .
- 1864 - The U.S. Congress passes the Coinage Act which mandates that the inscription " In God We Trust " be placed on all coins minted as United States Currency .
- Benjamin Harrison opens the Unassigned Lands in what is now central Oklahoma to white settlement.
- begins a Blockade of Cuba n ports and the USS Nashville captures a Spanish merchant ship.
- 1912 - '' Pravda ,'' the "voice" of the Communist Party Of The Soviet Union , begins publications in Saint Petersburg .
- 1914 - Babe Ruth , age 19, pitches his first professional game for the minor league Baltimore Orioles .
- 1915 - The Use Of Poison Gas In World War I escalates when Chlorine Gas is released as a Chemical Weapon in the Second Battle Of Ypres .
- 1930 - The United Kingdom , Japan and the United States sign the London Naval Treaty regulating Submarine warfare and limiting Shipbuilding .
- 1943 - Albert Hofmann writes his first report about the hallucinogenic properties of LSD .
- initiated – Allied forces land in the Hollandia area of New Guinea .
- forces have taken Eberswalde without a fight, Adolf Hitler admits defeat in his underground Bunker and states that Suicide is his only recourse.
- 1946 - The first installment of the popular Japan ese comic strip, '' Sazae-san '', is published in the Fukunichi Shimbun .
- begin.
- 1964 - The 1964-1965 New York World's Fair opens for its first season.
- 1970 - First Earth Day celebrated.
- 1971 - John Kerry , dressed in combat fatigues, testifies on his views of the Vietnam War before the United States Senate Foreign Relations Committee
- bombing in Vietnam prompts antiwar protests in New York City , San Francisco , and Los Angeles .
- 1975 - Barbara Walters signs a five-year $5 million contract with the American Broadcasting Corporation (ABC), becoming the highest paid Television newsperson.
- 1978 - The Blues Brothers make their first appearance on '' Saturday Night Live ''.
- 1979 - Brent Mydland performs his first show with the Grateful Dead at Spartan Stadium , San Jose, California .
- 1992 - 1992 Explosion In Guadalajara , Mexico ; 206 people were killed, nearly 500 injured and 15,000 were left homeless
- 1993 - In Washington, DC , the Holocaust Memorial Museum is dedicated.
- 1993 - The Web Browser Mosaic version 1.0 is released.
- 1996 - Cisco Systems acquires StrataCom for $4B.
- 1997 - Haouch Khemisti Massacre in Algeria ; 93 villagers killed.
- 1997 - A 126-day hostage crisis at the residence of the Japan ese Ambassador in Lima , Peru ends after Government commandos storm and capture the building, rescuing 71 hostages. One hostage dies of a Heart Attack , two soldiers are killed from rebel fire, and all 14 rebels are slain.
- 2000 - In a predawn raid, federal agents seize six-year-old Elián González from his relatives' home in Miami, Florida .
- 2000 - The Big Number Change takes place in the United Kingdom .
- 2004 - Two fuel trains collide in Ryongchon , North Korea , killing up to 150 people.
- 2006 - 243 people were injured in pro-democracy protest in Nepal after Nepali security forces opened fire on protesters against King Gyanendra .
- 2006 - Newcastle striker and local hero Alan Shearer retired from football 3 matches early due to an injury
- 1451 - Queen Isabella Of Castile and Leon (d. 1504 )
- 1550 - Edward De Vere , Lord Great Chamberlain of England (d. 1604 )
- 1610 - Pope Alexander VIII (d. 1691 )
- 1658 - Giuseppe Torelli , Italian composer (d. 1709 )
- 1690 - John Carteret, 2nd Earl Granville , English statesman (d. 1763 )
- 1692 - James Stirling , Scottish mathematician (d. 1770 )
- 1707 - Henry Fielding , English author (d. 1754 )
- 1711 - Eleazar Wheelock , American founder of Dartmouth College (d. 1779 )
- 1724 - Immanuel Kant , German philosopher (d. 1804 )
- 1766 - Madame De Staël , French author (d. 1817 )
- 1812 - Solomon Caesar Malan , British orientalist (d. 1894 )
- 1816 - Charles Denis Bourbaki , French general
- 1840 - Odilon Redon , French painter (d. 1916 )
- 1844 - Lewis Thornton Powell , would-be Assassin of Secretary Of State William Seward (d. 1865 )
- 1852 - Guillaume IV, Grand Duke Of Luxembourg (d. 1912 )
- 1854 - Henri La Fontaine , Belgian lawyer and activist, recipient of the Nobel Peace Prize (d. 1943 )
- 1860 - Ada Rehan , American stage actress (d. 1916 )
- 1870 (N.S.) - Vladimir Lenin , Russian revolutionary (d. 1924 )
- 1873 - Ellen Glasgow , American author (d. 1945 )
- 1876 - Robert Bárány , American physician, recipient of the Nobel Prize In Physiology Or Medicine (d. 1936 )
- 1876 - Georg Lurich , Estonian wrestler (d. 1920 )
- 1881 - Alexander Kerensky , Russian politician (d. 1970 )
- 1884 - Otto Rank , Austrian psychologist (d. 1939 )
- 1891 - Harold Jeffreys , English astronomer (d. 1989 )
- 1899 - Vladimir Nabokov , Russian writer (d. 1977 )
- 1904 - Robert Oppenheimer , American physicist (d. 1967 )
- 1906 - Eddie Albert , American actor (d. 2005 )
- 1906 - Prince Gustaf Adolf, Duke Of Westrobothnia , second in line to the Swedish throne (d. 1946 )
- 1907 - Ivan Efremov , Russian paleontologist and author (d. 1972 )
- 1909 - Rita Levi-Montalcini , Italian neurologist, recipient of the Nobel Prize In Physiology Or Medicine
- 1910 - Norman Steenrod , American mathematician (d. 1971 )
- 1912 - Kathleen Ferrier , British contralto (d. 1953 )
- 1914 - Jan De Hartog , Dutch writer (d. 2002 )
- 1916 - Yehudi Menuhin , American-born violinist (d. 1999 )
- 1918 - Mickey Vernon , baseball player
- 1919 - Donald J. Cram , American chemist, Nobel Prize laureate (d. 2001 )
- 1922 - Charles Mingus , American musician (d. 1979 )
- 1922 - Wolf V. Vishniac , American microbiologist (d. 1973 )
- 1923 - Bettie Page , American model
- 1923 - Aaron Spelling , American television producer and writer
- 1925 - George Cole , British actor
- 1926 - Charlotte Rae , American actress
- 1926 - James Stirling , British architect (d. 1992 )
- 1935 - Paul Chambers , American jazz bassist (d. 1969 )
- 1936 - Glen Campbell , American musician
- 1937 - Jack Nicholson , American actor
- 1937 - Jack Nitzsche , American composer and arranger (d. 2000 )
- 1939 - Jason Miller , American actor (d. 2001 )
- 1943 - Louise Glück , American poet
- 1944 - Steve Fossett , American adventurer
- 1946 - John Waters , American film writer and director
- 1950 - Peter Frampton , British musician
- 1950 - Zygi Wilf , owner of the Minnesota Vikings
- 1951 - Paul Carrack , British keyboardist, singer and songwriter
- 1952 - Marilyn Chambers , American actress
- 1958 - Ken Olandt , American actor
- 1959 - Catherine Mary Stewart , Canadian actress
- 1959 - Ryan Stiles , Canadian-born actor and comedian
- 1962 - Jeff Minter , British video game programmer
- 1965 - Peter Zezel , Canadian ice hockey player
- 1966 - Mariana Levy , Mexican actress (d. 2005 )
- 1967 - Sheryl Lee , American actress
- 1967 - Harvey Williams , American football player
- 1968 - Zarley Zalapski , Canadian ice hockey player
- 1970 - Andrea Giani , Italian volleyball player
- 1972 - Owen Finegan , Australian International Rugby Union
- 1974 - Shavo Odadjian , Armenian-born bassist ( System Of A Down )
- 1975 - Greg Moore , Canadian race car driver (d. 1999 )
- 1979 - Daniel Johns , lead singer of Australian band Silverchair
- 1980 - Courtney Friel , presenter of World Poker Tour
- 1981 - Ken Dorsey , American football player
- 1982 - Kaká , Brazilian footballer
- 1983 - Matt Jones , American football player
- 1984 - Amelle Berrabah , singer in UK band Sugababes
- 1984 - Paul Hopper , ICMA legend ICMA
- 1986 - Justin Pogge , Ice hockey player
- 296 - Pope Caius
- 536 - Pope Agapetus I
- 1592 - Bartolomeo Ammanati , Italian architect and sculptor (b. 1511 )
- 1672 - Georg Stiernhielm , Swedish poet (b. 1598 )
- 1699 - Hans Erasmus Aßmann, Freiherr Von Abschatz , German statesman and poet (b. 1646 )
- 1758 - Antoine De Jussieu , French naturalist (b. 1686 )
- 1778 - James Hargreaves , English weaver, carpenter, and inventor (b. 1720 )
- 1806 - Pierre-Charles Villeneuve , French admiral (stabbed) (b. 1763 )
- 1833 - Richard Trevithick , English inventor (b. 1771 )
- 1892 - Edouard Lalo , French composer (b. 1823 )
- 1896 - Thomas Meik , British civil engineer (b. 1812 )
- 1908 - Henry Campbell-Bannerman , Prime Minister Of The United Kingdom (b. 1836 )
- 1925 - André Caplet , French composer (b. 1878 )
- 1930 - Jeppe Aakjaer , Danish poet and novelist {b. 1866 )
- 1945 - Käthe Kollwitz , German artist (b. 1867 )
- 1946 - Harlan F. Stone , Chief Justice Of The United States Supreme Court (b. 1872 )
- 1951 - Horace Donisthorpe , British entomologist (b. 1870 )
- 1968 - Stephen H. Sholes , American recording executive (b. 1911 )
- 1978 - Will Geer , American actor and activist (b. 1902 )
- 1980 - Jane Froman , American actor and singer (b. 1907 )
- 1980 - Fritz Strassmann , German physicist (b. 1902 )
- 1983 - Earl "Fatha" Hines , British jazz pianist (b. 1903 )
- 1984 - Ansel Adams , American photographer (b. 1902 )
- 1985 - Paul H. Emmett , American chemical engineer (b. 1900 )
- 1986 - Mircea Eliade , Romanian writer and philosopher (b. 1907 )
- 1994 - Richard Nixon , President Of The United States (b. 1913 )
- 1995 - Maggie Kuhn , American activist (b. 1905 )
- 1996 - Erma Bombeck , American humorist and writer (b. 1927 )
- 2002 - Linda Lovelace , American actress (b. 1949 )
- 2003 - Martha Griffiths , U.S. Congresswoman (b. 1912 )
- 2003 - Michael Larrabee , American athlete (b. 1933 )
- 2004 - Pat Tillman , American football player and U.S. Army Ranger (killed in action) (b. 1976 )
- 2005 - Philip Morrison , American physicist (b. 1915 )
- 2005 - Erika Fuchs , German translator (b. 1906 )
- 2006 - Alida Valli , Italian actress (b. 1921 )
April 21 - April 23 - March 22 - May 22 – Listing Of All Days
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