Amylin's normal role in the body is unknown, although rodent amylin Knockout s are known to fail to achieve the normal Anorexia following food consumption. Because it is an Amidated peptide, like many Neuropeptide s, it is believed to be responsible for the anorectic effect.
is also the name of a San Diego -based pharmaceutical company which began with the premise of using amylin as a hormone-replacement therapy for type II diabetics. Although it was unable to develop amylin for that purpose due to its amyloidogenicity, it did successfully market Symlin which uses the same strategy; and also markets Byetta , a completely different drug for diabetics.
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