- Absolute Debugger , a general purpose debugger for UNIX platforms
- Active Dimension Battle , a battle system in computer gaming
- Adnan Menderes Airport , the IATA airport code for the airport in Izmir, Turkey
- Advanced Digital Broadcast , supplier of digital TV set-top-boxes for cable, satellite, terrestrial and telecommunications
- African Development Bank , a non-profit financial institution whose aim is to help developing African countries
- Allgemeine Deutsche Biographie , a biographical reference work in the German language
- Apple Desktop Bus , a bit-serial computer bus for connecting low-speed devices to computers
- Asian Development Bank , a non-profit financial institution whose aim is to help developing Asian countries
- ADB is also a file format used by Microsoft Access
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